[Video Profile] Interview with Michael Fons, VP Corporate Development at Inovio Biomedical
Written by Doug Cress on Nov 25, 2008
Inovio Biomedical’s electroporation technology uses brief, controlled electrical pulses to increase cellular uptake of gene expression in DNA-based treatments; this enhances the potency of DNA-based immunotherapies against cancers and infectious diseases.
Inovio has an extensive patent portfolio and line of devices and prototypes for electroporation-based DNA delivery. Interim clinical data from multiple studies has indicated safety and tolerability, heightened levels of antibody and T-cell immune responses, and durable local and systemic tumor responses – providing initial validation of electroporation’s ability to enhance DNA vaccine potency.
The company licenses its technology and works through collaboration. Current partners include:
- Merck (cancers)
- Wyeth (infectious diseases)
- HIV Vaccine Trial Network (HIV)
- National Cancer Institute (HIV)
- International AIDS Vaccine Initiative (HIV)
- Vical (metastatic melanoma)
- Moffitt Cancer Center (malignant melanoma)
- University of Southampton (prostate cancer)



