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12481 High Bluff Drive, Suite 150 San Diego, CA 92130 USA phone:858-480-2420 fax:877-393-3519
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| www.calixainc.com
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| Research Sector |
Biotech Specialty Pharma |
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| Summary Description |
| Calixa developshospital-based antibiotics to treat infections resulting from resistant strains of bacteria. |
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| Management |
| Eckard Weber, M.D., President and CEO; James (Yigong) Ge, Ph.D., M.D., Executive Vice President and CSO; Ian Friedland, M.D., Chief Medical Officer; Lynne R. Rollins, CFO. |
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| Keywords |
| antibiotics, resistant, infections, bacteria |
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| Description |
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A biopharmaceutical company focused on the development of a novel cephalosporin to address the expanding problem of multi-drug resistant organisms. Treatment of infections caused by resistant gram-negative bacteria, especially Pseudomonas aeruginosa, is recognized as an unmet medical need by the infectious diseases community.
Calixa's lead product, CXA-101, is an IV formulation of a novel cephalosporin that has excellent potency especially against multi-drug resistant Pseudomonas aeruginosa, which differentiates it from other cephalosporins. No similar drug is known to be in development. Calixa plans to combine this product with a b-lactamase inhibitor; the combination product (CXA-201) has the potential to become the first-line therapeutic choice for hospitalized patients suffering from serious infection caused by gram-negative organisms. |
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