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Clavis Pharma
Biotech Specialty Pharma
Parkveien 53 B
Oslo, NO-0256 Norway
phone:+47 24 11 09 50
fax:(47) 24 11 09 51
Symbol CLAVIS
Exchange OSL
Founded 2001
Employees
www.clavispharma.com
Research Sector Biotech Specialty Pharma
Summary Description
Using lipid vector technology to develop pharmaceuticals.
Management
Geir Christian Melen, Chief Executive Officer; Ole Henrik Eriksen, Chief Operating Officer; Gunnar Manum, Chief Financial Officer; Jan Alfheim, Chief Business Officer; Bo I. Nilsson, Chief Medical Officer
Ownership
Financials


* numbers in thousands
 

Keywords
elacytarabine, gemcitabine, leukaemia, intravenous, myelodysplastic

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Updated: Jan. 14, 2010

Description
Clavis Pharma develops new and superior pharmaceuticals by leveraging the potential of its Lipid Vector Technology, LVT.
Products / Services
Clavis lead development candidate, CP-4055 is an LVT derivative of cytarabine (Ara-C), an approved cytotoxic drug used to treat blood cancers. Clavis second development candidate in oncology, CP-4126, is an LVT derivative of gemcitabine (Gemzar). CP-4010 and CP-4018 are LVT derivatives of acyclovir and ganciclovir respectively. Acyclovir (Zovirax) is a key drug in the treatment of herpes and shingles while Ganciclovir (Cytovene) is a potent drug used for the treatment of cytomegalovirus.
Technology / Differentiation
Clavis Pharma's LVT implies chemical binding of certain fatty acids to pharmaceutical agents, thereby creating new chemical entities with improved biological properties such as increased cellular uptake, reduced toxicity and slow release of the active compound. The company has demonstrated LVT's potential to improve drug performance and to open new indications for existing pharmaceuticals in a variety of therapeutic areas such as cancer and viral diseases.


2012-02-05-491