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29, rue Lect, Meyrin
Geneva, CH-1217 Switzerland
phone:41-22-719-0900
fax:41-22-719-0909
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Private |
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| www.spinx-technologies.com
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| Research Sector |
Medical Devices & Tech |
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| Summary Description |
| Products using programmable microfluidics technology. |
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| Management |
| Bart Van de Vyver, Ph.D., Founder, CEO; Piero Zucchelli, Ph.D., Founder, CSO |
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| Keywords |
| Micro-fluid technology, Automated diagnostics |
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| Description |
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SpinX designs and develops products which utilizing its programmable microfluidics technology. Their platform offers a fully integrated solution which reduces manual work, while avoiding complex and costly robotics infrastructures, and can be used in a wide variety of applications, from drug discovery to consumer diagnostics. |
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| Products / Services |
The SpinX Lab is the first practical way to transition from low volume microplate assays to a fully automated bench-top technology for assays in nanoliter volumes.
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| Technology / Differentiation |
SpinX technology is based on an adaptive microfluidics technology in which the user chooses the exact dilution, mixing and incubation conditions in real time. The pluripotent design of the microfluidic system means that specific assays chosen from a broad range of applications can be run using the same microfluidics card. This is enabled by SpinX's core technology, the Virtual Laser Valve.
The Virtual Laser Valve (VLV) technology enables the SpinX? gCards? to be user-programmed to suit a broad range of applications. A VLV connects two microfluidic structures at a precise location on the gCard which defines a precise volume of liquid. By applying centrifugal force at a controlled time, liquid moves through this newly created connection to a new chamber, where it can be combined with other liquids to create precise dilutions or biochemical reactions for controlled incubation times.
The dosimeter is the VLV-based microfluidic component used to meter liquid volumes. It consists of a chamber on one side of the base and one or more channels on the other side of the base. The channels are oriented in the direction of the centrifugal force acting on the liquid. Initially, liquid is contained in the chamber. The VLV then creates a connection between the chamber and one of the channels. The volume of liquid which will flow through this connection is precisely determined by the cross section of the chamber multiplied by the difference between the initial and resulting liquid level. If the initial liquid level is not known, it can be defined by first creating a VLV, with the excess liquid purged.
The multiplexer is the VLV-based microfluidic component used to connect a given input of liquid to a given output. It consists of two sets of parallel channels, located on opposite sides of the base, with the second set of channels running perpendicular to the first set. By operating the VLV, a series of connections is created between specific channels on opposite sides of the base, literally laying down a path for the liquid to follow.
The SpinX cards contain several rows of dosimeters, separated by multiplexers. Any assay or set of assays can be built up by moving the appropriate volumes of liquid to specific destinations, where they are mixed together before using the result in the next step.
Various independent aspects of SpinX?s core technology and its implementation ? ranging from materials and processes to principles and devices ? have been protected worldwide. The intellectual property portfolio is available for licensing for select markets. |
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Biotech & Specialty Pharma
Healthcare Services
Medical Devices & Tech
OneMedPlace Member
AdvaMed Members