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XenoPort
Biotech Specialty Pharma
3410 Central Expressway
Santa Clara, CA 95051 USA
phone:(408) 616-7200
fax:(408) 616-7210
Symbol XNPT
Exchange NASDAQ
Founded 0
Employees
www.xenoport.com
Research Sector Biotech Specialty Pharma
Summary Description
Improving the oral absorption, distribution and pharmacokinetics of drugs.
Management
Ronald W. Barrett, Ph.D., Chief Executive Officer and Director; William J. Rieflin, President; William G. Harris, Senior Vice President of Finance and Chief Financial Officer; Kenneth C. Cundy, Ph.D., Senior Vice President of Preclinical Development; Mark A. Gallop, Ph.D., Senior Vice President of Research; David R. Savello, Ph.D., Senior Vice President of Development; Pierre V. Tr?n, M.D., M.M.M., Senior Vice President and Chief Medical Officer
Ownership
Financials


* numbers in thousands
 

Keywords
nutrients, gastroin, testinal, sub optimal drug, bloodstream, relies

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Updated: Apr. 15, 2011

Description
Xenoport, Inc. is focused on developing products that harness the body's intrinsic transport systems to improve the oral absorption, distribution and pharmacokinetics of drugs.
Technology / Differentiation
XenoPort's proprietary Transported Prodrug technology utilizes the body's natural mechanisms for actively transporting nutrients through cellular barriers. Our scientists identify specific, high-capacity nutrient transporter proteins found in cells that line the gastrointestinal, or GI, tract. Using this information, they chemically modify the structure of a suboptimal drug to create a Transported Prodrug that utilizes these transporters to gain efficient absorption into the bloodstream through active transport. Once in the blood stream, our Transported Prodrugs are engineered to split apart, releasing the drug and natural substances that generally have well-studied, favorable safety characteristics.
Strategy
XenoPort is currently applying its technology to off-patent drugs to provide new, patentable compounds with improved medicinal properties; and the company plans to work collaboratively with pharmaceutical companies to improve the pharmacokinetic properties of their proprietary drug candidates.
Funding
Since its inception, XenoPort has raised over $127 million in private venture funding. XenoPort's investors include AIG SunAmerica Ventures, Alejandro Zaffaroni, Arch Venture Partners, CMEA Ventures, Frazier Healthcare Ventures, HBM BioVentures AG, Lilly BioVentures, Lombard Odier & Cie, Lotus BioScience Ventures, Novartis BioVentures Ltd., Orbimed Advisors, Skyline Ventures, The Invus Group, Venrock Associates and WestRiver Capital.


2012-02-08-1163